Optimized technique allows B cells to be transfected with extraneous DNA without the use of viruses

The introduction of foreign DNA into human cells through a process known as 'transfection' allows scientists to study gene expression in the laboratory and enables clinicians to treat genetic diseases. The methods commonly used for this procedure work for most cell types, except when it comes to B cells—a group of infection-fighting white blood cells in the immune system that have proven extremely difficult to transfect without the use of viruses. Viruses, however, pose a number of safety issues.

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