Controlling the transition between generations
Thursday, September 18, 2014 - 08:40
in Biology & Nature
Rafal Ciosk and his group at the FMI have identified an important regulator of the transition from germ cell to embryonic cell. LIN-41 prevents the premature onset of embryonic transcription in oocytes poised for embryonic development, thus ensuring a successful passage between generations. This finding also holds promise for efforts to reprogram differentiated human cells into induced pluripotent stem cells.