Researchers suppress cell division in prostate tumour tissue through enzyme inhibition
Tuesday, February 5, 2013 - 08:40
in Health & Medicine
A previously poorly investigated signalling pathway is crucial for the growth and proliferation of prostate cancer cells. An international research team discovered this when studying the enzyme "soluble adenylyl cyclase" that produces the second messenger molecule cAMP. When the scientists inhibited the enzyme, the cancer cell proliferation was suppressed. The team led by Dr. Yury Ladilov from the Department of Clinical Pharmacology at the Ruhr-Universität Bochum reported together with colleagues from the Department of Urology at the RUB and the Cornell University in New York in the Journal of Biological Chemistry.