Balancing trastuzumab's survival benefits and heart risks for women with breast cancer
Tuesday, April 17, 2012 - 21:01
in Health & Medicine
Adding trastuzumab (trade name Herceptin) to the treatment offered to women who have HER2-positive breast cancer, significantly increases the chance of life being prolonged, and reduces the chance of tumours reappearing once therapy stops. This is important, because about one-fifth of women who develop early breast cancer have HER2-positive tumours that, if untreated, are associated with a worse outlook than HER2-negative tumours. At the same time, however, women given trastuzumab have a higher risk of experiencing problems with their heart. These findings are the key conclusions of a systematic review published in The Cochrane Library.