Optogenetic tool elucidated: Researchers explain channelrhodopsin

Controlling nerve cells with the aid of light: this is made possible by optogenetics. It enables, for example, the investigation of neurobiological processes with unprecedented spatial and temporal precision. The key tool of optogenetics is the light-activated protein channelrhodopsin. Biophysicists from Bochum and Berlin have now succeeded in explaining the switching mechanism through an interdisciplinary approach. The researchers report on their findings in the Journal of Biological Chemistry.

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