Crystalizing the foundations of better antihistamines
Monday, November 21, 2011 - 09:30
in Biology & Nature
Researchers in Japan have solved the structure of a complex between the antihistamine drug doxepin and its target receptor histamine H1 receptor (H1R)1. Led by So Iwata of Kyoto University and the RIKEN Systems and Structural Biology Center in Yokohama, the teams findings should aid the development of better treatments for allergies and inflammation.