Nuclear receptors battle it out during metamorphosis in new fruit fly model
Thursday, October 6, 2011 - 12:30
in Biology & Nature
Growing up just got more complicated. Thomas Jefferson University biochemistry researchers have shown for the first time that the receptor for a major insect molting hormone doesn't activate and repress genes as once thought. In fact, it only activates genes, and it is out-competed by a heme-binding receptor to repress the same genes during the larval to pupal transition in the fruit fly.