Multi-omics strategy gives systems-level insight toward Salmonella pathogenesis
Tuesday, September 20, 2011 - 08:30
in Biology & Nature
Researchers from Pacific Northwest National Laboratory and Oregon Health & Science University combined extensive omics measurements with a novel computational network analysis approach to better understand the complex regulatory interactions in the pathogen Salmonella Typhimurium and identify virulence-related proteins that cause systemic infection in a host. Their results, which appeared in BMC Systems Biology, demonstrate the utility of this approach to infectious disease research and offer new biological insights that may lead to new prevention and treatment strategies.