Immune system malfunction may trigger inflammatory bowel disease

Friday, May 13, 2011 - 05:00 in Health & Medicine

In a finding that could have implications for the prevention and treatment of inflammatory bowel disease (IBD), Yale University researchers have identified a previously unknown sensor regulating the composition of certain intestinal bacterial microflora (the microbes that live in our gut). They also found the absence of this regulating sensor results in a dramatic alteration of the microbial environment of the intestines – increasing the risk of developing IBD. The study is available online in Cell on May 12, and will appear in the May 27 print edition.

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