MicroRNA mediates gene-diet interaction related to obesity

Wednesday, April 20, 2011 - 16:30 in Biology & Nature

Eating more n-3 polyunsaturated fatty acids, commonly known as omega-3 fatty acids, may help carriers of a genetic variant on the perilipin 4 (PLIN4) gene locus lose weight more efficiently. Based on this observation, researchers at the Jean Mayer Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University identified a microRNA (miRNA) which may elucidate the underlying biological mechanism.

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