Ensembles of neurons in the brain's hippocampus inform about future as well as past experiences

Friday, March 25, 2011 - 09:00 in Biology & Nature

When a mammal explores an unfamiliar environment, ensembles of ‘place’ cells in the hippocampus fire individually, recording specific locations in a cognitive map that aid future spatial navigation of the area. Once the relationship between place cell activity and location has been established, the activity of the cells can be used to predict the animal’s location within its environment. Activity patterns in the ensembles are later ‘replayed’ during rest and sleep, and neuroscientists believe this is important for consolidating the spatial memories of the new environment.

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