Novel factor behind ES cells' neural default

Wednesday, March 16, 2011 - 10:01 in Biology & Nature

Embryonic stem cells (ESCs) are highly regarded for their ability to give rise to the full range of cellular lineages found in the adult body, but left to their own devices ESCs tend to differentiate into neural lineages. Researchers from RIKEN have revealed how the nuclear protein Zfp521 is key to the default neural fate.

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