'Oncometabolite' linked with widespread alterations in gene expression
Tuesday, January 18, 2011 - 12:06
in Health & Medicine
A new study finds that a metabolite commonly elevated in brain cancer and leukemia may promote tumorigenesis by altering the expression of a large number of genes. New research, published by Cell Press in the January 18th issue of the journal Cancer Cell, enhances the understanding of the link between metabolic deregulation and cancer and may help to guide development of new targeted cancer therapies.