The secrets behind stress-induced illness

Wednesday, December 22, 2010 - 09:33 in Health & Medicine

(PhysOrg.com) -- Both humans and animals have different reactions to stress. Ongoing exposure to stress causes some individuals to show symptoms of disease, while others are resilient and do not become ill. For a long time, the reasons behind these different reactions have been unclear. Now, scientists working with mice at the Max Planck Institute of Psychiatry have identified the molecular composition of the AMPA receptor, a common binding site in the central nervous system, as a possible cause of the differences. The neurotransmitter glutamate, which is responsible for the mediation of nerve impulses, binds to this receptor. In future, this discovery may help to predict individual risk for stress-related diseases.

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