New mutation linked to non-Hodgkin's lymphoma

Some patients with non-Hodgkin lymphoma (NHL) -- a cancer of B cells -- harbor a particular mutation in the gene encoding the receptor for B cell activating factor (BAFF), according to a paper published online on November 1 in the Journal of Experimental Medicine. BAFF, a soluble protein needed for B cell survival and maturation, is elevated in the blood of some NHL patients and is associated with poor prognosis.

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