Key action of a gene linked to both Alzheimer's disease and type 2 diabetes identified
Tuesday, September 28, 2010 - 17:07
in Health & Medicine
A research team led by Mount Sinai School of Medicine has identified the mechanism behind a single gene linked to the causes of both Alzheimer's disease and Type 2 diabetes. The data show that a gene for a protein called SorCS1, which can cause Type 2 diabetes, impacts the accumulation of amyloid-beta (Abeta) in the brain. Abeta plays a key role in the development of Alzheimer's disease. The study is published in the September 29th issue of the Journal of Neuroscience.