Hypertensive rat genome sequence expected to uncover genetic basis of human hypertension

Chronic high blood pressure, also known as hypertension, is a serious health risk factor that afflicts more than 25% of all adults worldwide, but the molecular basis of the disease remains poorly understood. In a study published online today in Genome Research, scientists have sequenced the genome of the spontaneously hypertensive rat, building a rich catalog of genetic variants that will help researchers to understand causes of the disease in humans.

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