Chemists Clarify Protein-Receptor Complex`s Role in Iron Uptake to Cells

(PhysOrg.com) -- In recent years cancer researchers, particularly brain tumor specialists, have pinned some hope for delivering anti-tumor drugs on transferrin, a protein that carries the essential element iron into cells. This is because unlike most other proteins, transferrin can cross the blood-brain barrier. But a new study of transferrin and its receptor by chemists at the University of Massachusetts Amherst reveals that transferrin isn`t as open to drug loading as hoped, so creating a good delivery system may be more challenging than previously thought.

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