Adding Common Genetic Variants to Breast Cancer Risk Models Offers Only Small Benefit

(PhysOrg.com) -- Scientists report that breast cancer risk assessment models, which predict a woman's chance of developing breast cancer, do not perform better when they include common inherited genetic variants recently linked to the disease. Therefore, recommendations for breast cancer screening or treatments will remain unchanged for most women. The study, led by investigators from the National Cancer Institute (NCI), part of the National Institutes of Health, appears in the March 18, 2010, New England Journal of Medicine.

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