Examining alcohol use disorders through gene networks instead of individual genes

Tuesday, March 2, 2010 - 02:14 in Biology & Nature

Alcohol use disorders (AUDs) are influenced by multiple genetic, environmental and behavioral factors, which makes it difficult to find individual genetic markers to help identify those at risk of developing AUDs. This study examined how a person's level of response (LR) to alcohol, which is closely linked to the development of AUDs, is related to "gene sets" rather than individual genes. Findings show that glutamate receptor signaling genes that enable brain cells to respond to chemicals, and then to communicate that response, are involved in a person's LR.

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