Canine morphology: Hunting for genes and tracking mutations

Why do domestic dogs vary so much in size, shape, coat texture, color and patterning? Study of the dog genome has reached a point where the molecular mechanisms governing such variation across mammalian species are becoming understood. In an essay published in the March 2, 2010 issue of PLoS Biology, National Human Genome Research Institute (NHGRI) researchers discuss advances in understanding the genomic mechanisms controlling canine morphology.

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