Helicobacter pylori and EBV in gastric carcinomas
Wednesday, February 10, 2010 - 01:28
in Health & Medicine
Mechanisms of gastric carcinogenesis are still not yet understood. Studies have linked genetic and epigenetic factors or microbiological agents to gastric cancer, but they didn't look for these events together. Dr. Ferrasi from Brazil verified the methylation profile, microsatellite instability (MSI), Helicobacter pylori status and Epstein Barr virus infection in gastric cancer samples. Intestinal and diffuse adenocarcinoma showed different methylation profiles and an association was found between methylation and Helicobacter pylori-cagA+.