An etiological role for H. pylori in autoimmune gastritis

Autoimmune type atrophic gastritis is a severe gastric atrophy associated with vitamin B12 deficiency. The reason for the disappearance of acid secreting cells from gastric mucosa is not fully understood, but the role of Helicobacter pylori in initiating the mucosal damage is suspected in animal studies. A study found signs of previous H. pylori infection in patients with autoimmune type atrophic gastritis.

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