I-1c gene therapy: Not such a good idea in heart failure?

Tuesday, January 12, 2010 - 07:49 in Health & Medicine

Several lines of evidence, including the observation that the protein I-1 is downregulated in human failing hearts, have led to the suggestion that gene therapy to express a constitutively active form of the protein (I-1c) might provide a new approach to treating heart failure.

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