Interstitial macrophages: immune cells that prevent asthma

The continual presence in the air of the microbe-derived molecule LPS promotes asthma in some individuals. What prevents inhalation of LPS from promoting asthma in most individuals is not well understood. However, researchers have now ascribed this function in mice to a population of lung immune cells known as lung interstitial macrophages (IMs); this is the first in vivo function described for these cells.

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