Polycystins : proteins that regulate the cellular barometer
Thursday, November 5, 2009 - 17:20
in Biology & Nature
What is the role of proteins called polycystins in patients with polycystic kidney disease? A team of researchers from CNRS and INSERM, led by Eric Honoré from the Institut de Pharmacologie Moléculaire et Cellulaire (France) has elucidated the molecular and cellular mechanisms linked to polycystin malfunctions that cause this common hereditary disease. In a study published on October 30, 2009 in the journal Cell, Honoré and his colleagues reveal a new biological function for polycystins in regulating pressure sensing.