The 2 faces of Mdmx: Why some tumors don't respond to radiation and chemotherapy

Monday, July 6, 2009 - 12:21 in Health & Medicine

A tightly controlled system of checks and balances ensures that a powerful tumor suppressor called p53 keeps a tight lid on unchecked cell growth but doesn't wreak havoc in healthy cells. In their latest study, scientists at the Salk Institute for Biological Studies suggest just how finely tuned the system is and how little it takes to tip the balance.

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