Gene may 'bypass' disease-linked mitochondrial defects, fly study suggests
Tuesday, May 5, 2009 - 13:49
in Biology & Nature
By lending them a gene normally reserved for other classes of animals, researchers have shown they can rescue flies from their Parkinson's-like symptoms, including movement defects and excess free radicals produced in power-generating cellular components called mitochondria. The gene swap also protects healthy flies' mitochondria, and to a large extent the flies themselves, from the damaging effects of cyanide and other toxins, the team reports in the May issue of Cell Metabolism, a Cell Press publication.