Intestinal parasites alter immunity in cholera patients

Cholera patients also infected with parasitic intestinal worms have a significantly reduced immune response to the cholera toxin, according to a report published March 31st in the open-access journal PLoS Neglected Tropical Diseases. Results of the study from a collaborative team led by researchers at Massachusetts General Hospital (MGH) and the International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B) suggest that parasitic infection could reduce immunity to future cholera infection and may compromise the effectiveness of cholera vaccines.

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