HIV-1 protease inhibitor induced oxidative stress in pancreatic B-cells: thymoquinone protection
Wednesday, March 25, 2009 - 12:21
in Health & Medicine
Researchers at the Tulane University School of Medicine, New Orleans, Louisiana have discovered that the HIV-1 protease inhibitors (PIs), such as nelfinavir included in highly active antiretroviral therapy (HAART) regimen for the treatment of HIV-1 patients, induce deleterious effects on insulin secretion mediated through the oxidative stress pathway.