Brain deletion of FK506-binding protein enhances repetitive behaviors in mice

A new study reveals a link between dysregulation of a common signaling pathway and repetitive behaviors similar to those associated with multiple neurological and neurodegenerative disorders including, autism spectrum disorders, obsessive compulsive disorder, schizophrenia, and Huntington's disease. The research, published by Cell Press in the December 11th issue of the journal Neuron, identifies a critical role for a molecule linked to immunosuppression in learning, memory, and repetitive behavior and may lead to the development of new treatments for perseverative behaviors.

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