Estrogen and progesterone receptor isoforms expression in the stomach of Mongolian gerbils

Gerbils were treated with estradiol and E2+ progesterone. Stomach proteins were immunoblotted for Estrogen-alpha, ER-beta, progesterone receptor-A, PR-B. ER-alpha, PR-A and PR-B were detected. PR isoforms were not regulated by hormones. E2 down-regulated ER-alpha in corpus. This suggests that E2 and P4 actions in stomach are mediated by their nuclear receptors.

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