Enzyme for ubiquitin-dependent protein degradation linked to cellular senescence

Thursday, May 22, 2008 - 13:21 in Biology & Nature

A new study, published by Cell Press in the May 23rd issue of the journal Molecular Cell, identifies a pivotal role for the CUL7 E3 ubiquitin ligase in growth control. The research makes an exciting new connection between the regulation of protein degradation and the initiation of cellular senescence.

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