Sedative May Reduce Duration of Mechanical Ventilation, Improve Comfort for ICU Patients
Tuesday, March 20, 2012 - 16:00
in Health & Medicine
The results of two randomized trials indicate that among intensive care unit (ICU) patients receiving prolonged mechanical ventilation, use of the sedative dexmedetomidine was not inferior (outcome not worse than treatment compared to) to the standard sedatives midazolam and propofol in maintaining light to moderate sedation; also, dexmedetomidine reduced the duration of mechanical ventilation compared with midazolam, and improved patients' ability to communicate pain compared with the other drugs, according to a study in the March 21 issue of JAMA.