Building a Better Protein
Monday, February 23, 2009 - 15:56
in Physics & Chemistry
Scientists are searching for ways to increase the stability of proteins. In new research published in the Proceedings of the National Academy of Sciences, Rensselaer Senior Constellation Professor George Makhatadze and his colleagues detail a targeted strategy to substantially increase the thermodynamic stability of nearly any protein, while preserving its unique function. Their redesign technique creates proteins that remain stable at temperatures 10 degrees Celsius higher than normal.
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