Behind the FDA's 'black box' warnings

Friday, August 15, 2008 - 19:56 in Health & Medicine

Cipro and the similar antibiotics are given the agency's strictest label, while epilepsy drugs Lyrica, Depakote and Topamax may have escaped. Why? TWO GROUPS of drugs were under the Food and Drug Administration spotlight last month. Both have been associated with rare but serious side effects, and both were candidates for a "black box" warning, the strongest the FDA issues short of taking a drug off the market. Although one was hit with this safety advisory, the other may have escaped. We look at these drugs and their different fates.

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