Something doesn’t smell right

Wednesday, January 15, 2014 - 18:30 in Biology & Nature

For most animals, the scent of rotting meat is powerfully repulsive. But for others, such as carrion-feeding vultures and insects, it’s a scent that can be just as powerfully attractive. The question of why some animals are repelled and others attracted to a particular scent, scientists say, gets at one of the most basic and poorly understood mysteries in neuroscience: How does the brain encode likes and dislikes? Harvard scientists say they’re closer to unraveling that question with the discovery of the first receptors in any species evolved to detect cadaverine and, two of the chemical byproducts responsible for the distinctive — and to most creatures repulsive — smell of rotting flesh. The study is described in a paper published in the Proceedings of the National Academy of Sciences. “This is the first time we’ve identified a receptor for these chemicals,” said Associate Professor of Cell Biology Stephen Liberles, a senior author of...

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