New function of a bacterial photoresponsive protein: Resisting adhesion of mammalian cells

Thursday, March 1, 2012 - 18:00 in Physics & Chemistry

Non-fouling materials that resist cell adhesion are very important in fundamental research on cell–biomaterial interactions and for practical applications. Thus, they have been extensively investigated during the last decade. Natural biomacromolecules such as bovine serum albumin (BSA) have conventionally been used to block cell adhesion. Zhao and Ding (Fudan University, Shanghai, China) recently reported that the purple membrane (PM) containing a natural photoresponsive protein, bacteriorhodopsin (BR), can serve as a new basic substance that resists adhesion of mammalian cells.

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