New class of ‘dancing’ dendritic cells derived from blood monocytes

The discovery of a new class of dendritic cells that stem from blood monocytes in mice promises to accelerate research into clinical therapies that use these cells, known to be the sentinels of the immune system. Much research has been done on classical dendritic cells, which are found in the lymph tissues of mice. But these are hard to come by in the case of humans. The new technique may allow the generation of “authentic” dendritic cells from human blood samples, however, which could make it much easier to advance dendritic cell-based vaccines and cancer treatments that are under development now.

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