Genetic profiling reveals genes active in the earliest brain circuit construction
Friday, May 29, 2009 - 16:00
in Biology & Nature
Screening for genes that guide the earliest formation of the embryonic brain, researchers identified 229 specifically responsible for subplate neurons, which form the initial scaffolding for assembling cortical circuits. The work indicates the breadth of factors involved in initial neurogenesis and provides investigators with a biochemical handle to start investigating the various contributions.