How Living Cells Generate Complexity - Hidden Splicing Code

Wednesday, May 5, 2010 - 13:30 in Biology & Nature

Researchers writing in Nature say they can have discovered how living cells use a limited number of genes to generate enormously complex organs such as the brain. The team describes how a hidden code within DNA explains how a limited number of human genes can produce a vastly greater number of genetic messages. The discovery bridges a decade-old gap between our understanding of the genome and the activity of complex processes within cells, and could one day help predict or prevent diseases such as cancers and neurodegenerative disorders. The researchers developed a new computer-assisted biological analysis method that finds 'codewords' hidden within the genome that constitute what is referred to as a 'splicing code'. read more

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