Major discovery on the mechanism of drug resistance in leukemia and other cancers

A mechanism that enables the development of resistance to Acute Myeloid Leukemia (AML) anticancer drugs, thereby leading to relapse, has been identified by researchers. The new discovery constitutes a major breakthrough in the fight against AML, one of the deadliest forms of leukemia, because it immediately suggests strategies to overcome drug resistance. Furthermore, the type of drug resistance the team identified is likely implicated in other cancers and a successful new treatment regimen based on these findings could have broad applications in treating cancer.

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