Scientists have discovered that the gas nitric oxide (NO), produced in all cells of the human body for natural purposes, plays a fundamental regulatory role in controlling bacterial function, via a signaling mechanism called S-nitrosylation (SNO), which binds NO to protein molecules. In addition, the researchers discovered a novel set of 150 genes that regulate SNO production and disruption of these genes created bacterial cell damage resembling the cell damage seen in many common human diseases. Collectively these data point to new classes of antibiotics and several new disease treatments.
- Discovery of earliest life forms' operation promises new therapies for key diseasesThu, 26 Apr 2012, 16:27:08 EDT
- In rare disease, a familiar protein disrupts gene functionTue, 26 May 2009, 20:36:08 EDT
- Mount Sinai finds promising clue to mechanism behind gene mutation that causes Parkinson's diseaseFri, 25 Mar 2011, 10:03:12 EDT
- In a rare disorder, a familiar protein disrupts gene functionTue, 26 May 2009, 20:36:11 EDT
- New research into the mechanisms of gene regulationThu, 19 Nov 2009, 15:51:58 EST