Successful treatment for mice with beta-thalassemia

Beta-thalassemia is an inherited blood disorder that results in chronic anemia. A major complication of the condition is iron overload, which has been linked to low levels of the protein hepcidin. New research indicates that increasing the concentration of hepcidin in beta-thalassemic mice limits iron overload and markedly reduces their anemia, pointing to a potential new therapeutic approach to limiting iron overload and mitigating anemia in patients with beta-thalassemia.

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