Possible 'persistence' switch for tuberculosis found: Computer model finds probable genetic mechanism for TB dormancy

A model for the genetic "persistence" switch that toggles tuberculosis bacteria into a dormant state that resists antibiotics and immune system responses is described in a new study. An analysis of stress-response genes in the organism Mycobacterium tuberculosis has allowed bioengineers to zero in on a gene network that appears to help the bacteria ward off attacks.

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