With just one enzyme missing, mice show 'global' metabolic improvements
Wednesday, March 3, 2010 - 23:35
in Biology & Nature
When researchers created mice lacking an enzyme that breaks down and releases stored triglycerides, they expected to see animals with better lipid profiles. But according to a new study, they got more than they bargained for. The triacylglycerol hydrolase (TGH)-deficient mice showed global metabolic benefits, with essentially no downside.