Disrupting Male Fertility
Tuesday, November 17, 2009 - 20:14
in Health & Medicine
The sexual function of male rodents can be impaired by in utero and/or neonatal exposure to external molecules such as DES that disrupt normal hormone functioning, giving rise to concerns that low-level exposure to such molecules might cause similar effects in humans. New research, to be published in the Journal of Clinical Investigation, has determined the molecular mechanism underlying many of the harmful effects of DES on the mouse testis.