Common Herbicides And Fibrates Block Nutrient-sensing Receptor Found In Gut And Pancreas
Friday, October 9, 2009 - 12:14
in Biology & Nature
Certain common herbicides and lipid-lowering fibrate drugs act in humans to block T1R3, a nutrient-sensing taste receptor also present in intestine and pancreas. These compounds were not previously known to act on the receptor, which influences glucose homeostasis and energy metabolism. The effect is specific to humans and not revealed during animal testing.