Gene Shut-down May Offer Early Warning Of Chronic Leukemia

A new study shows that certain genes are turned off early in the development of chronic lymphocytic leukemia (CLL), before clinical signs of the disease appear. The study examined cancer cells from CLL patients and from a new strain of mice that develops a very similar disease. The findings suggest that epigenetic alterations might serve as markers for detecting CLL early and for monitoring progression, and that their reversal might delay or prevent progression.

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