Gene Mutation Increases Drug Toxicity, Rejection Risk In Pediatric Kidney Transplants

Screening for mutations in a gene that helps the body metabolize a kidney transplant anti-rejection drug may predict which children are at higher risk for side effects, including compromised white blood cell count or organ rejection, according to new research. This genetic approach could also help physicians tailor personalized anti-rejection drug doses to prevent adverse reactions, according to researchers.

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